CIMP

 

Cancer 

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Ren L, Liu C, Çifcibaşı K, Ballmann M, Rammes G, Mota Reyes C, Tokalov S, Klingl A, Grünert J, Goyal K, Neckel PH, Mattheus U, Schoeps B, Yıldızhan SE, Sezerman OU, Cevik NC, Sever EA, Karakas D, Safak O, Steiger K, Muckenhuber A, Görgülü K, Chen Z, Zhang J, Ye L, Maula Ali MI, Tiwari VK, Romanyuk N, Giesert F, Saur D, Rad R, Schmid RM, Algül H, Krüger A, Friess H, Ceyhan GO, Istvanffy R, Demir IE. Sensory neurons drive pancreatic cancer progression through glutamatergic neuron–cancer pseudo-synapses. Cancer Cell. 2025 Sep 25;S1535-6108(25)00395-2. doi: 10.1016/j.ccell.2025.09.003. 

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Adel Jensen L, Bækgaard CH, Larsen MB, Boonen SE, Bak Jylling AM, Hikmat Z, Hao Q, van Overeem Hansen T, Pedersen IS, Larsen MJ, Thomassen M. Preliminary evaluation of ShallowHRD performance compared to HRDetect in familial breast cancer tumors. Sci Rep. 2025 Aug 11;15(1):29442. doi: 10.1038/s41598-025-14122-9. 

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Inayatullah M, Dwivedi AK, Tiwari VK. Advances in single-cell omics: transformative applications in basic and clinical research. Curr Opin Cell Biol. 2025 Aug;95:102548. doi: 10.1016/j.ceb.2025.102548. 

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Do TTN, Block I, Burton M, Sørensen KP, Larsen MJ, Jylling AMB, Ejlertsen B, Lænkholm AV, Tan Q, Kruse TA, Thomassen M. Multi-transcriptomics predicts clinical outcome in systemically untreated breast cancer patients with extensive follow-up. Breast Cancer Res. 2025 Jul 15;27(1):133. doi: 10.1186/s13058-025-02061-2. 

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Kostov AM, Jensen MB, Ejlertsen B, Thomassen M, Rossing M, Pedersen IS, Petersen AH, Christensen LL, Wadt KAW, Berrocal-Almanza LC, Miranda M, Lænkholm AV. Timely germline BRCA testing after invasive breast cancer promotes contralateral risk-reducing mastectomy and improves survival: an observational retrospective study. Breast Cancer Res. Treat. 2025 Jul;212(2):309–323. doi: 10.1007/s10549-025-07726-2. 

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Munch AK, Feldner ES, Bækgaard CH, Larsen MB, Slemming-Adamsen N, Boonen DS, Møller NB, Pedersen IS, Hansen TVO, Terkelsen T, Burton M, Hao Q, Boonen SE, Thomassen M. Classification of gene variants in a Danish population with suspected predisposition to hereditary breast and/or ovarian cancer. Cancers (Basel). 2025 May 29;17(11):1819. doi: 10.3390/cancers17111819. 

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Stojanovic L, Abbotts R, Tripathi K, Coon CM, Rajendran S, Abbasi Farid E, Hostetter G, Guarnieri JW, Wallace DC, Liu S, Wan J, Calendo G, Marker R, Gohari Z, Inayatullah MMA, Tiwari VK, Kader T, Santagata S, Drapkin R, Kommoss S, Pfisterer J, Konecny GE, Coopergard R, Issa JJ, Winterhoff BJN, Topper MJ, Sandusky GE, Miller KD, Baylin SB, Nephew KP, Rassool FV. ZNFX1 functions as a master regulator of epigenetically induced pathogen mimicry and inflammasome signaling in cancer. Cancer Res. 2025 Apr 3;85(7):1183–1198. doi: 10.1158/0008-5472.CAN-24-1286. 

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Kostov AM, Jensen MB, Ejlertsen B, Thomassen M, Rossing CM, Pedersen IS, Petersen AH, Christensen LL, Wadt KAW, Lænkholm AV. Germline BRCA testing in Denmark following invasive breast cancer: progress since 2000. Acta Oncol. 2025 Jan 28;64:147–155. doi: 10.2340/1651-226X.2025.42418. 

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Lusby R, Demirdizen E, Inayatullah M, Kundu P, Maiques O, Zhang Z, Terp MG, Sanz-Moreno V, Tiwari VK. Pan-cancer drivers of metastasis. Mol Cancer. 2025 Jan 2;24(1):2. doi: 10.1186/s12943-024-02182-w. 

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Neurology 

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Waede M, Kingo C, Damsbo K, Joergensen MU, Oubounyt M, Gjerstorff M, Thomassen M, Moeller JB, Baumbach J, Elkjaer ML, Illes Z. Phenotypic changes in a monocyte cluster with high interleukin-1 beta expression during long-term anti-CD20 therapy. Ann Neurol. 2025 Aug 29. doi: 10.1002/ana.78004. 

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Ngo A, Liu L, Larivière S, Kebets V, Fett S, Weber CF, Royer J, Yu E, Rodríguez-Cruces R, Zhang Z, Ooi LQR, Yeo BTT, Frauscher B, Paquola C, Caligiuri ME, Gambardella A, Concha L, Keller SS, Cendes F, Yasuda CL, Bonilha L, Gleichgerrcht E, Focke NK, Kotikalapudi R, O'Brien TJ, Sinclair B, Vivash L, Desmond PM, Lui E, Vaudano AE, Meletti S, Kälviäinen R, Soltanian-Zadeh H, Winston GP, Tiwari VK, Kreilkamp BAK, Lenge M, Guerrini R, Hamandi K, Rüber T, Bauer T, Devinsky O, Striano P, Kaestner E, Hatton SN, Caciagli L, Kirschner M, Duncan JS, Thompson PM, McDonald CR, Sisodiya SM, Bernasconi N, Bernasconi A, Gan-Or Z, Bernhardt BC. Associations between epilepsy-related polygenic risk and brain morphology in childhood. Brain. 2025 Aug 14:awaf259. doi: 10.1093/brain/awaf259. 

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Dwivedi AK, Mahesh A, Sanfeliu A, Larkin J, Siwicki RA, Sweeney KJ, O'Brien DF, Widdess-Walsh P, Picelli S, Henshall DC, Tiwari VK. High-resolution multimodal profiling of human epileptic brain activity via explanted depth electrodes. JCI Insight. 2025 Jan 9;10(1):e184518. doi: 10.1172/jci.insight.184518. 

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Waede M, Voss LF, Kingo C, Moeller JB, Elkjaer ML, Illes Z. Longitudinal analysis of peripheral immune cells in patients with multiple sclerosis treated with anti-CD20 therapy. Ann Clin Transl Neurol. 2024 Oct;11(10):2657–2672. doi: 10.1002/acn3.52182. 

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Elkjaer ML, Hartebrodt A, Oubounyt M, Weber A, Vitved L, Reynolds R, Thomassen M, Rottger R, Baumbach J, Illes Z. Single-cell multi-omics map of cell type-specific mechanistic drivers of multiple sclerosis lesions. Neurol Neuroimmunol Neuroinflamm. 2024 May;11(3):e200213. doi: 10.1212/NXI.0000000000200213. 

 

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Bone / Osteoporosis 

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El-Masri BM, Andreasen CM, Laursen KS, Kofod VB, Dahl XG, Nielsen MH, Thomsen JS, Brüel A, Sørensen MS, Hansen LJ, Kim AS, Taylor VE, Massarotti C, McDonald MM, You X, Charles JF, Delaisse JM, Andersen TL. Mapping RANKL- and OPG-expressing cells in bone tissue: the bone surface cells as activators of osteoclastogenesis and promoters of the denosumab rebound effect. Bone Res. 2024;12:62. doi: 10.1038/s41413-024-00362-4.